Epithalon
Tetrapeptide telomere regulator (AEDG). Longevity research.
Specification
- Catalogue ID: SP114
- Listed purity specification: 99.5%
- Formulation: Lyophilized
- Quantity: 10mg / Vial
- Price: £49.00
Telomerase research · epigenetic regulation · peptide bioregulator
Epithalon (Ala-Glu-Asp-Gly; AEDG) is a synthetic tetrapeptide bioregulator developed from research at the St. Petersburg Institute of Bioregulation and Gerontology in the 1980s and 1990s. It was designed as a synthetic analogue of Epithalamin, a peptide fraction isolated from bovine pineal gland extract.
In vitro, Epithalon has been investigated as a potential telomerase activator. Published cell-culture studies have reported its apparent ability to increase telomerase activity and elongate telomere sequences in somatic cell lines — findings that generated interest within the peptide-bioregulator and longevity-research communities.
The compound has also been studied in relation to epigenetic regulation — specifically, chromatin remodelling and modulation of gene expression associated with cell-cycle control in in-vitro ageing models, and effects on the Bax/Bcl-2 apoptotic pathway ratio in cell culture.
No physiological or therapeutic properties are claimed; supplied for in-vitro laboratory research use only.
Compound identity
- CAS number: 307297-39-8
- Molecular formula: C₁₄H₂₂N₄O₉
- Molecular weight: 390.35 Da
- Sequence: AEDG
- Solubility: Soluble in water at ≥1 mg/mL
- Reconstitution: Add 1 mL bacteriostatic water per 10 mg; swirl gently
For in-vitro laboratory research use only. Not for human or veterinary use, consumption, or therapeutic application. No medical claims are made.