Cagrilintide
Long-acting amylin analogue studied in vitro.
Specification
- Catalogue ID: SP109
- Listed purity specification: 99.7%
- Formulation: Lyophilized
- Quantity: 5mg / Vial
- Price: £160.00
Amylin / CGRP receptor research · long-acting amylin analogue
Cagrilintide is a long-acting synthetic amylin analogue designed for extended receptor engagement at the amylin receptor (AMY) and calcitonin gene-related peptide receptor (CGRP-R). It incorporates a fatty-acid side chain modification that confers prolonged albumin binding and an extended pharmacokinetic profile compared to native amylin.
In vitro, cagrilintide has been studied for receptor binding at AMY1-3 (amylin receptor subtypes comprising calcitonin receptor with RAMP subunits) and CGRP-R, both Gαs-coupled GPCRs. Cell-based assays have examined its Gαs/cAMP signalling and β-arrestin recruitment profile in recombinant receptor systems.
No physiological or therapeutic properties are claimed; supplied strictly as a research reagent for in-vitro laboratory use only. Offered solely as an unlicensed research compound.
Compound identity
- Molecular formula: C₁₇₄H₂₇₆N₅₄O₅₇S₃
- Molecular weight: 4155.54 Da
- Solubility: Soluble in water at acidic to neutral pH
- Reconstitution: Reconstitute in bacteriostatic water; swirl gently
For in-vitro laboratory research use only. Not for human or veterinary use, consumption, or therapeutic application. No medical claims are made.